Expected Outcome: Reducing dependencies of critical and strategic raw materials through partial or total substitution by safe and sustainable innovative advanced materials and/or via more efficient use of critical and strategic raw materials in production processes; Speeding up the innovation cycle within value chain(s) important for European industry; Enhancing competitiveness of the industries and operational costs, while making supply chains more secure; New or improved production processes, innovative advanced materials and products that are safer and more sustainable, supporting a clean and autonomous economy; and Demonstrating how the safe and sustainable by design (SSbD) chemicals and materials framework can guide innovation. Scope: The focus of this topic is on alternatives for the substitution or more efficient use of critical and strategic raw materials [1] . The design and development of innovative advanced materials (IAMs) and processes should lead to an innovation cycle covering the (re)design of materials and production processes, and the integration of IAMs into products. Proposals should develop IAMs or process technologies to replace or reduce the use of critical a
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